Immunolocalization Of Phosphodiesterase Isoenzymes In Rat Tissues Using Confocal Microscopy

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A New Phosphodiesterase in Rat Tissues

1. A phosphodiesterase that cleaves glycerophosphoinositol into glycerophosphate and inositol has been detected in rat tissues. 2. The enzyme requires Mg2+(Mn2+) and has a pH optimum of 7.7. 3. The richest sources of the enzyme are kidney and intestinal mucosa. In pancreas subcellular fractions it occurs largely in the microsomal fraction. 4. The enzyme is inhibited by excess substrate and by t...

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ژورنال

عنوان ژورنال: Microscopy and Microanalysis

سال: 2002

ISSN: 1431-9276,1435-8115

DOI: 10.1017/s143192760210208x